"Naan Ee" revolves around the life of a young woman named Anbu, played by Saravanan, who is struggling to find her place in the world. She meets a mysterious and charismatic radio jockey, Johnny (played by Sibiraj), who becomes her confidant and love interest. As their relationship deepens, Anbu's life takes a dramatic turn, and she finds herself entangled in a web of emotions, love, and deceit.