The movie picks up with John Rambo (Sylvester Stallone), a Vietnam War veteran who has been living a quiet life in Mexico. However, his peaceful existence is disrupted when he discovers that his friend, María (Adriana Paz), has been killed by a Mexican cartel. Rambo teams up with a local, Gabriel (Yancy Arias), and together they embark on a mission to avenge María's death and take down the cartel.
