"The 2nd Law" is characterized by its diverse range of musical styles, which blend elements of rock, pop, electronica, and classical music. The album features a more refined and polished production sound than Muse's earlier work, with a greater emphasis on atmospheric textures and electronic beats. Tracks like "Survival" and "Madness" showcase the band's ability to craft catchy, anthemic choruses, while songs like "The 2nd Law: Unnatural Selection" and "Follow Me" demonstrate a more experimental approach to songwriting.